Dynamic Cerebral Contrast-enhanced Perfusion MRI - Biomedical Signal Analysis: Contemporary Methods and Applications - page 309

(a) (b)

(c) (d)

Figure 11.3
Diffusion-weighted MR image and conventional perfusion parameter maps of the
same patient as in figures 11.1 and 11.2. (a) Diffusion weighted MR image; (b)
MTT map; (c) rCBV map; (d) rCBF map.

shown in figure 11.4b (white region). In addition, a symmetrical con-
tralateral ROI can be determined (light gray region). Then, the mean
CTC values of all the pixels in the ROIs are determined and visualized
in figure 11.4d, together with the corresponding quantitative perfusion
parameters: the difference between the affected (figure 11.4c) and the
nonaffected (figure 11.4d) sides with regard to CTC amplitude and dy-
namics is visualized, in agreement with highly differing corresponding
quantitative perfusion parameters. Comparative quantitative analyses
for fuzzy clustering based on deterministic annealing, the self-organizing