Biomedical Engineering Reference
In-Depth Information
O
P
O
-
P
OH
O
-
OH
O
O
P
OH
OH
e
-
e
-
e
-
AP
ES cell
Gold electrode
(B)
1. 0
0.5
0.0
1 mM
0.8 mM
0.6 mM
0.4 mM
0.2 mM
-0.5
-1.0
0.6
0.4
0.2
0.0
-0.2
Potential (V)
(C)
0.80
0.75
0.70
0.65
0.60
0.55
0.50
0.45
0.40
0.2
0.4
0.6
0.8
1. 0
NP concentration (mM)
Figure 19.4
Electrochemical detection of ESC differentiation [29]. (A) Schematic representation of
the electrochemical detection system used to monitor the differentiation of mouse ESCs. (B) Cyclic
voltammetry at different concentrations of 1-naphthyl phosphate (1-NP; from 0.2 m
m
to 1 m
m
) and a
scan rate of 100 mV s
−1
. (C) The reduction peak current increased linearly with 1-NP concentration.
Reproduced from Yea
et al
., 2013 with permission from Elsevier.
