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(
Torruella et al., 2012
).
Figure 9.8
shows a molecular phylogenetic tree of
opisthokonts (
Ruiz-Trillo et al., 2007
). The overall conclusion, subject to
the caveat of low statistical support, indicates a close relationship between
protist 3/3 SDgbs and the vertebrate Ngb subfamily. A molecular phyloge-
netic analysis of deuterostome SDgbs by
Hoffmann, Opazo, Hoogewijs,
et al. (2012)
has suggested at least four separate globin lineages, one of which
is related to Ngbs. Another recent study by one of us (X. B.) has provided
strong evidence for the presence of Ngb-related globins throughout the
metazoans, including placozoans, choanoflagellates, sponges and cnidarians
(
Lechauve et al., 2013
). The results shown in
Fig. 9.7
are in agreement with
the Bayesian tree, shown in
Fig. 9.9
, based on the Clustal Omega alignment
of 37 protist, 30 vertebrate, 7 plant and 41 lower eukaryotes, representing
urochordates, cephalochordates hemichordates, echinoderms, placozoans,
Figure 9.8 A phylogenetic tree of opisthokonts based on molecular data. From
Ruiz-
Trillo et al. (2007)
, with permission from Elsevier.
