Microbial Eukaryote Globins - Advances in Microbial Physiology - page 387

CHAPTER NINE

Microbial Eukaryote Globins

Serge N. Vinogradov * , Xavier Bailly † , David R. Smith { ,
Mariana Tinajero-Trejo } , Robert K. Poole } , David Hoogewijs },1
* Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, Detroit,
Michigan, USA
† Marine Plants and Biomolecules, Station Biologique de Roscoff, Roscoff, France
{ Department of Biology, Western University, London, Ontario, Canada
} Institute of Biology and Biotechnology, Department of Molecular Biology and Biotechnology, The University
of Sheffield, Sheffield, United Kingdom
} Institute of Physiology and Z¨ rich Center for Integrative Human Physiology, University of Z¨ rich, Z¨ rich,
Switzerland
1 Corresponding author: e-mail address: [e-mail]

Contents
1. Overview

393

2. Historical Perspective 394

3. Globin Nomenclature 395

4. Microbial Eukaryote Globins 397

4.1 Archaeplastida 397

4.2 SAR clade 402

4.3 Excavata 403

4.4 Amoebozoa 404

4.5 Other microbial eukaryotes 404

4.6 Opisthokonta 405

4.7 Fungi 406

5. Phylogenetic Relationships 406

5.1 Methods of globin identification and alignment 406

5.2 Multiple sequence alignments and phylogenetic analysis 409

5.3 Origin of protist globins and their relationship to higher eukaryote globins 411

6. Globin Function 420

6.1 Overview of globin functions 420

6.2 Yeasts 421

6.3 Other fungi 423

6.4 Protozoa 429

6.5 Algae 433

6.6 Perspectives 433

7. Conclusion 434

Acknowledgements 434

References 436