Biology Reference
In-Depth Information
Table 8.2 Amino acid residues building up the proximal (F8) and distal (B10, CD1, E7,
E11, E15 and G8) haem pocket of sperm whale Mb and TrHbs belonging to groups I, II
and III
Protein
Group
B10
CD1
E7
E11
E15
F8
G8
Sperm whale Mb
L
F
H V
L
H I
Nostoc commune
HFQLLHI
Paramecium caudatum
YFQTLHV
Chlamydomonas eugametos
I
Y
F
Q Q
L
H V
Synechocystis
YFQQLHV
Mycobacterium tuberculosis
N
Y
F
L
Q
F
H V
Mycobacterium avium
N
Y
F
L
Q
F
H V
Mycobacterium avium
O
Y
Y
A
L
L
H W
Mycobacterium tuberculosis
O
Y
Y
A
L
L
H W
Mycobacterium smegmatis
O
Y
Y
A
L
L
H W
Mycobacterium leprae
II
Y
Y
A
L
L
H W
Thermobifida fusca
YYALLHW
Bacillus subtilis
YFTQLHW
Arabidopsis thaliana
YFAQFHW
Thiobacillus ferrooxidans
YFHLWHW
Mycobacterium avium
P
Y
F
H M W H W
Campylobacter jejuni
III
Y
F
H I
W H W
Bordetella pertussis
1
Y
F
H L
W H W
Adapted from
Milani et al. (2005)
.
(
Lu, Egawa, Wainwright, Poole, & Yeh, 2007; Nardini et al., 2006
), this
mechanism appears to be operative in the
C. jejuni
TrHbIII (
Nardini
et al., 2006
).
The sequence identity between TrHbs belonging to the three phyloge-
netic groups is very low (
<
20%) (
Nardini, Pesce, Milani, &Bolognesi, 2007;
Vuletich & Lecomte, 2006; Wittenberg et al., 2002
), but may be higher than
80% within a given group. Analysis of the distribution of TrHbs suggests a
scenario for the evolution of the different groups where the group II gene is
ancestral and group-I and group-III genes are the results of duplications and
transfer events (
Vuletich & Lecomte, 2006
).
