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Figure 5.3 Structure-based sequence alignment of group III (trHbP) haemoglobins of
Mycobacteria.
the regulation of either gene; there are no recognition sequences involved in
the response to stress or O
2
dependence (
Pawaria, Lama, Raje, & Dikshit,
2008
). Further study into the genetic regulation of the trHbs showed that the
organisation of the
glbN
gene is conserved in
M. tuberculosis
and
M. bovis
(
Couture et al., 1999; Ouellet et al., 2002
), and in other pathogenic
Mycobacteria such as
M. avium
(
Pawaria et al., 2008
; see
Fig. 5.4
). However,
