Biology Reference
In-Depth Information
Table 4.1 Selected bacterial haemoglobins: function(s) and regulation
Regulation
Heterologous expression
Environmental
factors and/or
compounds
involved in
upregulation
Family,
sub-family
and globin
name
Function(s)
inferred by
mutation/
complementation
Crystal
structure
solved
Regulator(s)
involved in
natural host
Function(s)
inferred
Organism
Host
References
E. coli
WT
a
Escherichia coli
M
FHb
Hmp
Yes
O
2
-dependent
NO
detoxification to
nitrate
(alleviation of
NO toxicity)
Fnr, MetR,
NsrR
Nitrosative
stress
Oxidative stress
resistance, NO
consumption,
increased cell
growth in
microaerophilic
conditions
Anjum, Ioannidis, and
Poole (1998)
,
Bodenmiller
and Spiro (2006)
,
Bollinger, Bailey, and
Kallio (2001)
,
Corker and
Poole (2003)
,
Cruz-Ramos
et al. (2002)
,
Flatley et al.
(2005)
,
Frey, Farres,
Bollinger, and Kallio
(2002)
,
Gardner and
Gardner (2002)
,
Gardner,
Costantino, and Salzman
(1998)
,
Gardner, Gardner,
Martin, and Salzman
(1998)
,
Hausladen, Gow,
and Stamler (1998)
,
Hernandez-Urzua et al.
(2003)
,
Ilari, Ceci, Ferrari,
Rossi, and Chiancone
(2002)
,
Justino, Vicente,
