Biology Reference
In-Depth Information
sepsislike illness. The HRC index is a unitless number between 0 and
1 proportional to the risk of an acute clinical deterioration in the next
24 hours. The HRC index: (1) Showed highly significant association with
impending sepsis and sepsislike illness (p<0.001); and (2) added
significantly to the demographic information of BW, GA, and days of
postnatal age in predicting sepsis and sepsislike illness (p<0.001). The
conclusion from this clinical trial was that continuous HRC monitoring
is a generally valid and potentially useful noninvasive tool in the early
diagnosis of neonatal sepsis and sepsislike illness. Additional details
regarding the clinical trial and the exact definition of the HRC index can
be found in Griffin et al. (2003).
E
XERCISE
6-10
For an RRI series with low SampEn, what additional tests could be used
to determine whether there is an increased proportion of decelerations
(of interest in predicting sepsis) or accelerations? Could you suggest two
such tests?
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