Biology Reference
In-Depth Information
24 weeks gestation, and weighed 720 g at birth. The baby had evidence
of lung disease but was clinically stable when the HR observations
began. The three plots in Figure 6-3 illustrate normal HRV and the
abnormal changes occurring before sepsis.
600
500
400
300
A
600
500
400
300
B
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500
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300
0
512
1024
1536
2048
2560
3072
3584
4096
C
Time [RR interval number]
FIGURE 6-3.
Plot of RRI time series. The three panels are from the same infant while clinically stable (panel A)
and from 18 (panel B) and 9 (panel C) hours before an acute clinical deterioration leading to death.
(From Kovatchev, B. P., Farhy, L. S., Hanging, C., Griffin, M. P., Lake, D. E., Moorman, J. R. [2003].
Sample asymmetry analysis of heart rate characteristics with application to neonatal sepsis and
systemic inflammatory response syndrome. Pediatric Research, 54, 892-898. Used by permission.)
