Biology Reference
In-Depth Information
Hypoglycemia related car crash death
8
7
6
High-risk threshold
5
4
3
−
3
−
2
−
1
0
Crash
A
Months before crash
Hypoglycemia related ATV crash death
8
7
6
High-risk threshold
5
4
3
−
2
−
1
0
Crash
B
Months before crash
FIGURE 5-12.
The LBGI of two people with T1DM who died in an automobile crash and an ATV accident later
attributed to hypoglycemia. It is seen that the risk increased in the months prior to their accidents.
Should the researchers get in touch with the patient's physician to
suggest a change in medical management? Or should they simply allow
events to take their course without intervening?
There are strict government guidelines addressing these issues. Before
any new study with human subjects begins, a detailed protocol needs to
be worked out to address every aspect of the study, from recruiting
methods, to data collection procedures, confidentiality issues,
information-sharing, and documenting and reporting of adverse events.
Academic institutions where human subjects research is performed are
required to have human investigation committees (or institutional
review boards) that examine the protocols and rule on the suitability
of the proposed procedures, taking into account both the expected
