Biology Reference
In-Depth Information
The following statistics were computed for each participant at the end of
the study:
Mean value and standard deviation of all BG readings
Maximal BG range (calculated as the difference Maximal
Minimal
value for each subject)
LBGI
HBGI
Our goal is to compare the T1DM group with the T2DM group with
respect to these variables and basic statistics. Put in a different way,
instead of comparing a specific person with T1DM with a specific person
with T2DM as we did before, we now want to compare the ''average
person with T1DM'' with the ''average person with T2DM'' and assess
the similarities and differences. As before, we would like to verify
that LBGI and HBGI for the T1DM group are substantially (and
statistically significantly) higher than those for the T2DM group.
In Chapter 4, we examined the problem of group comparisons in terms
of their average values and the specifics of performing a t-test. We shall
apply the same statistical procedure here. We use t-test to reject (at a
specified confidence level p) the null hypothesis for equality of the group
averages. The smaller the p-value we choose, the smaller the chance
we will reject the null hypothesis when it is, in fact, true.
Table 5-2 presents the mean values for the T1DM and T2DM groups and
the results of performing a t-test. The last column contains both the
T1DM -
Mean (SD)
T2DM -
Mean (SD)
Variable
Significance
A: Glycemic control averages
HbA
1c
at 1.5 months
¼
¼
9.6 (1.2)
9.7 (1.2)
t
0.7, p
0.48
HbA
1c
at 3 months
9.2 (1.2)
9.3 (1.1)
t
¼
1.6, p
¼
0.11
Average BG
10.2 (1.9)
10.4 (2.2)
t
¼
1.5, p
¼
0.13
BG Standard deviation
4.8 (0.9)
3.3 (1.0)
t
¼
18.3, p<0.0001
B: Blood glucose range
Minimal BG (mmol/L)
2.2 (0.7)
3.4 (1.2)
t
¼
15.0, p<0.0001
Maximal BG (mmol/L)
24.9 (3.8)
21.2 (4.3)
t
¼
11.0, p<0.0001
BG Range (mmol/L)
22.7 (3.9)
17.8 (4.5)
t
¼
14.1, p<0.0001
C: Risk characteristics
Low BG Index
2.7 (2.0)
0.8 (1.1)
t
¼
14.5, p<0.0001
¼
¼
High BG Index
13.1 (5.8)
12.0 (7.1)
t
2.0, p
0.05
TABLE 5-2.
Group comparisons of T1DM versus T2DM subjects.
