Biology Reference
In-Depth Information
We assume:
1. The probability that a particular susceptible is infected by a
particular infective is p (again implying the groups are uniformly
mixed).
2. The number of susceptibles is denoted by S and the number
of infectives by I.
With these assumptions, the expected number of susceptibles that do not
interact with an infective is S
I
.
ð
1
p
Þ
C. Idea 3
There are some facts from calculus we now apply:
1. If x is close to 0, then e
x
1
þ
x;
2. If p is close to 0, then ln
ð
1
p
Þ
p;
0, then x
Y
e
ln
ð
x
Y
Þ
¼
e
Y ln
ð
x
Þ
.
3. If x
>
¼
I
We want to find an expression for S
ð
1
p
Þ
that is easier to work with.
From 3 above:
I
e
I ln
ð
1
p
Þ
:
ð
1
p
Þ
¼
Now, if p is close to 0, then ln
ð
1
p
Þ
is close to
p. Thus:
e
I ln
ð
1
p
Þ
e
Ip
If, in addition to p being close to 0, Ip is also close to 0, then we would
have:
e
Ip
1
Ip
Therefore, under these assumptions,
I
ð
Þ
ð
Þ:
S
1
p
S
1
pI
So, where does the differential equation come from? We explain this
through a discrete model. To construct our difference equation, we let:
S
n
¼
the number of susceptibles at the n-th stage
:
I
n
¼
the number of infectives at the n-th stage
:
The disease spreads when a susceptible interacts with an infective. So
S
n
þ
1
is the number of susceptibles in the n-th stage who did not interact
with an infective. According to our work above:
S
n
þ
1
¼
S
n
ð
1
pI
n
Þ¼
S
n
pS
n
I
n
;