Biology Reference
In-Depth Information
We assume:
1. The probability that a particular susceptible is infected by a
particular infective is p (again implying the groups are uniformly
mixed).
2. The number of susceptibles is denoted by S and the number
of infectives by I.
With these assumptions, the expected number of susceptibles that do not
interact with an infective is S
I .
ð
1
p
Þ
C. Idea 3
There are some facts from calculus we now apply:
1. If x is close to 0, then e x
1
þ
x;
2. If p is close to 0, then ln
ð
1
p
Þ
p;
0, then x Y
e ln ð x Y
Þ ¼
e Y ln ð x Þ .
3. If x
>
¼
I
We want to find an expression for S
ð
1
p
Þ
that is easier to work with.
From 3 above:
I
e I ln ð 1 p Þ :
ð
1
p
Þ
¼
Now, if p is close to 0, then ln
ð
1
p
Þ
is close to
p. Thus:
e I ln ð 1 p Þ
e Ip
If, in addition to p being close to 0, Ip is also close to 0, then we would
have:
e Ip
1
Ip
Therefore, under these assumptions,
I
ð
Þ
ð
Þ:
S
1
p
S
1
pI
So, where does the differential equation come from? We explain this
through a discrete model. To construct our difference equation, we let:
S n ¼
the number of susceptibles at the n-th stage
:
I n ¼
the number of infectives at the n-th stage
:
The disease spreads when a susceptible interacts with an infective. So
S n þ 1 is the number of susceptibles in the n-th stage who did not interact
with an infective. According to our work above:
S n þ 1
¼
S n
ð
1
pI n
Þ¼
S n
pS n I n
;
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