Biology Reference
In-Depth Information
0.5
0.5
0.5
PG
PED
CAST
0.4
phe
0.4
0.4
0.3
0.3
0.3
pro
leu
orn
phe
pro
val
pro
leu
0.2
0.2
0.2
phe
val
orn
leu
orn
val
0.1
0.1
0.1
0
0
0
-0.1
-0.1
-0.1
NH
2
Orn
Val
O
O
H
N
N
N
H
N
H
Pro
H
H
O
H
O
N
H
O
O
N
O
H
O
H
H
H
H
N
α
H
N
H
H
D-Phe
H
O
O
Leu
OH
gramicidin S
H
2
N
HO
OH
HO
O
HO
C
OH
O
OH
C
O
HO
OH
HO
HO
O
HO
O
O
O
OH
O
HO
C
O
O
HO
CO
C
O
OH
O
C
O
HO
HO
O
O
O
OH
O
O
O
HO
OH
HO
O
O
OH
HO
OH
OH
HO
OH
pentagalloylglucose (PG)
P = 160, biphenyl bond = 0
HO
HO
O
HO
OH
OH
HO
O
HO
1-
O
-galloylpedunculagin (PED)
P = 0.14, biphenyl bond = 2
O
O
OH
O
HO
HO
O
O
H
O
O
HO
O
OH
castalagin (CAST)
P = 0.02, biphenyl bond = 3
HO
OH
Fig. 4.5 Chemical shift change of gramicidin S in the presence of tannins; P = partition
coefficient.
HO
HO
OH
OH
