Electrospun Nanofibers for Regenerative Medicine - Soft Fibrillar Materials: Fabrication and Applications - page 260

Dura mater

Tendon-to-bone insersion site
Tendon-to-bone

Tendon

Bone

Cardiac muscle

Collagen
Mineral
Proteoglycans

Tendon

Sciatic nerve bundle

Figure 9.1 Illustration of some typical examples of tissues in the human body whose re-
generation would benefit from the use of nanofiber-based scaffolds with anisotropic struc-
tures that could be readily fabricated by electrospinning.

in vivo . We also highlight the applications of nanofiber-based scaffolds in four
different areas that involve nerves, dural tissues, tendons, and the tendon-to-bone
insertion site.

9.2
Electrospinning of Nanofibers

9.2.1
Setup and Principle

Four major components are required for electrospinning (Figure 9.2, center): [13]
a spinneret (e.g., a hypodermic needle with blunt-tip), a syringe pump for ejecting