Chemistry Reference
In-Depth Information
Based on these features, we
first propose a qualitative explanation for the long
sliding distance in muscle. It is known that muscle can modulate its motion
depending on the conditions. For example, the sliding distance (interacting distance)
between actin andmyosin
laments at low loads is
ten-fold as long as that of a single
myosin motor [72
-
74]. How can such a long sliding distance be achieved by
the cooperative action of multiplemyosinmotors? Upon rewinding the actin
lament,
we consider one head that interacts with the actin
filament andmoves it until the head
moves to the bottomend of the potential slope (Figure 2.10bmiddle and lower panels).
