Environmental Engineering Reference
In-Depth Information
Ta b l e 2
Extremolytes and their specific applications
Extremophilic
organisms
Compounds
Applications
References
Hydroxyectoine
Streptomyces
strain
Protection of oxidative protein damage
(LDH)
Reduction of VLS in immunotoxin
therapy
Stabilization of retroviral vaccines
Induction of thermotolerance in
E. Coli
Protection of
P. putida
against
anhydrobiotic stress
[1]
[6]
[24]
[63]
[64]
Ectoine
Halorhodospira
halochloris
Enzyme stabilization against heating,
freezing, and drying
Protection of LDH against heat and
freeze-thawing
Inhibition of insulin amyloid formation
Stabilization of tobacco cells against
hyperosmotic stress
Block of UVA-induced ceramide release
in human keratinocytes
Protection of the skin barrier against
water loss and drying out
Protection of skin immune cells against
UV radiation
Reduction of UV-induced SBCs
Prevention of UVA-induced photoaging
Cytoprotection of keratinocytes
[59]
[36]
[2]
[69]
[37]
[18]
[13]
[19]
[18]
[20]
Mannosylglycerate
Rhodothermus
marinus
Stabilization of enzymes against thermal
stress and freeze drying
Stabilization of recombinant nuclease
[16, 81]
[31]
DGP
Archaeoglobus
fulgidus
Thermostabilization of proteins and
rubredoxin
[55, 56]
Kahalalide F
Elysia rufescens/
Bryopsis
sp.
(mollusc/green
alga)
Treatment of patients with severe
psoriasis.
[40]
E7389
(halichondrin
B derivative)
Halichondria
okadai
(sponge,
synthetic)
Treatment for breast cancer
[3]
Curacin A
Lyngbya
majuscule
(cyanobac-
terium)
Potent inhibitor of cell growth and mitosis
[85]
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