Biomedical Engineering Reference
In-Depth Information
(
| ʸ )
Based on the arguments in Sect. B.4 of the Appendix, p
y
is derived such that
K
p
(
y
| ʸ ) =
p
(
y k | ʸ )
where
p
(
y k | ʸ ) = N(
y k |
0
, ʣ y ),
(5.25)
k
=
1
ʦ 1 in Eq. (B.30),
where
ʣ y is the model data covariance. Setting A to H and I to
we derive
ʣ y , such that
ʣ y = ʛ 1
AA T
+
.
(5.26)
According to Eq. (B.29), the log likelihood function is obtained as
K
K
K
2
1
2
| ʣ 1
y k ʣ 1
log p
(
y
| ʸ ) =
p
(
y k | ʸ ) =
log
|−
y k .
(5.27)
y
y
k
=
1
k
=
1
Using the matrix inversion formula in Eq. (C.91), we have
AA T 1
ʣ 1
y
ʛ 1
=
+
A A T
I 1
A T
ʓ 1 A T
= ʛ ʛ
ʛ
A
+
ʛ = ʛ ʛ
A
ʛ ,
(5.28)
Using the equation above and Eq. ( 5.11 ), we get
y k =
y k ʣ 1
y k
ʓ 1 A T
y k ʛ
u k ʓ ¯
y k =
ʛ ʛ
A
ʛ
y k − ¯
u k .
y
Also, since the relationship
| ʣ 1
y
ʓ 1 A T
ʓ 1 A T
|| ʛ |=| ʓ 1
|=| ʛ ʛ
A
ʛ |=|
I
ʛ
A
|| ʛ |
(5.29)
holds, 1 by substituting the above two equations into Eq. ( 5.27 ), we finally obtain the
expression for the likelihood:
K
K
K
K
2
log | ʛ |
1
2
1
2
y k ʛ
u k ʓ ¯
log p
(
y
| ʸ ) =
p
(
y k | ʸ ) =
| ʓ |
y k +
1 ¯
u k .
(5.30)
k
=
1
k
=
1
k
=
A more informative derivation of Eq. ( 5.30 ) uses the free energy expression in
Eq. (B.63) from the Appendix, which claims the following relationship holds:
1
ʓ 1 A T ,wehave
Defining C
=
I
ʛ
A
A T C = A T
A T
ʛ A ʓ 1 A T
= A T
( ʓ I ) ʓ 1 A T
= ʓ 1 A T
.
|=| ʓ 1
Taking the determinant of the equation above, we get
|
C
|
.
 
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