Environmental Engineering Reference
In-Depth Information
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Fig. 7.10 Flowcytometric analysis of MSCs before and after treatment with colloidal suspen-
sions: MSCs control (untreated cells), MSCs treated with fluid 2F, and MSCs treated with fluid 1F
SK-BR-3 tumor cells treated with each of the two colloidal suspensions
increased their aggressive potential by highly expressing Her2 oncoprotein on the
cellular surface (Fig.
7.11
). Another interesting aspect revealed by the
flowcytometric analysis is the translation of the SK-BR-3 cells to the left panel of
FCS axis and upper part of the SSC axis, suggestive for decreased size and
increased granularity of these cells treated with magnetite-based colloids. Data
are correlated with TEM images showing accumulation of nanoparticles within the
cytoplasm.
