In Silico QSAR-Based Predictions of Class I and Class II MHC Epitopes - Immunoinformatics - page 69

Table 3. Class I Additive-PLS Method: nonanchor residues related with strong and weak
binding for amino acids only.

Allele P1 P2 P3 P4 P5 P6 P7 P8 P9

Favored binding*
A*0101

Y T D H Y P N V AY

FLM
WY

A*0201 FY LM T FY I HP PQ V

A*0202 K L V M K MP FN FY LV

A*0203 DKW LM ANSV PT LRT I QV T L

A*0206 AK I L L L F F T V

A*0301 G IT F RT Y G IF M K

A*1101 S V M N V S F L K

A*3101 M L G P R R P E R

A*6801 Q A F F M L A L R

A*6802 F V IM CG P I PV R V

B*3501 F P I H T F L AK M

H2-D b AQF QS ILP CT N Q DE Y L

H2-K b

KS GISY RFY A F AG GPQ V

ADEP
GLSTV

ANILM
FSTWV

H2-K k F L P P F RLFW

Disfavored binding*
A*0101

F N K G D K A E D

A*0201 T T CEHS AFI R R GNQ DI S

A*0202 GI AV C N N QS ST DE AR

A*0203 DLR TV DFM ADLN SW D FLT DLQ A

A*0206 G M N E PY P V R A

A*0301 L N L E S K H E AQ

A*1101 L L A C R R L A Y

A*3101 Q A F T S F A R K

A*6801 A N G V V G R S Y

A*6802 K M STV S V G FQ D L

B*3501 T A QK S E V QS T TW

H2-D b LV E GS AIF G P GIMV CG Y

H2-K b

DLY DQL EHS GI LS FSV IFY M

NHIK
FWY

RDYQ
GHKP

H2-K k

A KS S K G DK

* A cut-off value of > +/- 0.3 is applied, with residues outside the limit in italics.