IMGT Standardization for Molecular Characterization of the T Cell Receptor/Peptide/MHC Complexes - Immunoinformatics - page 44

Table 4 . (continued)

(B) V-BETA CDR-IMGT interactions
V-BETA CDR1-IMGT

PDB Position G-ALPHA Peptide G-BETA

1j8h [5.] 27 M 10 K

28 D 76 A 10 K

29 H 10 K

37 E 72 A 73 V 76 A 10 K

38 N 69 A

1d9k [5.] 37 N 76 H

38 N 69 Q

V-BETA CDR2-IMGT

PDB Position G-ALPHA Peptide G-BETA

1j8h [.6.] 57 Y 65 Q 66 G 68 L 69 A 72 A

58 D 68 L 72 A 75 K

65 M 43 K 68 L

1d9k [.6.] 57 Y 65 Q 66 G 68 L 69 Q 72 A

V-BETA CDR3-IMGT

PDB Position G-ALPHA Peptide G-BETA

1j8h [.12] 108 S 73 V 10 K

109 T 69 A 70 N 73 V 5 K 7 N 8 T

110 G 73 V 8 T 9 L 10 K

112 L 10 K 58 Y

113 P 61A Q 62 D 63 L

1d9k [.11] 108 G 11 E

109 Q 11 E 58 Y 63 Y

110 G 10 W 11 E 63 Y 66 R

113 R 61 K 62 Q 63 Y 65 E 66 R

114 A 66 R

(C) V-ALPHA and V-BETA FR-IMGT interactions
V-ALPHA FR-IMGT

PDB Position G-ALPHA Peptide G-BETA

1j8h 55 K 62 D

1d9k 82 K 72 D

V-BETA FR-IMGT

PDB Position G-ALPHA Peptide G-BETA

1j8h 55 F 65 Q

66 K 43 K

67 E 43 K 65 Q

84 K 72 A 76 A 10 K

1d9k 55 Y 65 Q

66 T 43 K

67 E 43 K 65 Q 68 L

68 K 65 Q