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Fig. 2.
IMGT Colliers de Perles of the V-ALPHA and V-BETA domains from 1ao7 (IMGT/
3Dstructure-DB, http://imgt.cines.fr) (A) on one layer (B) on two layers. Amino acids are
shown in the one-letter abbreviation. Hydrophobic amino acids (hydropathy index with posi-
tive value) and tryptophan (W) found at a given position in more than 50% of analysed IG and
TR sequences are shown. The CDR-IMGTs are limited by amino acids shown in squares,
which belong to the neighbouring FR-IMGT and represent anchor positions. Hatched circles
correspond to missing positions according to the IMGT unique numbering (Lefranc et al.
2003b). Arrows indicate the direction of the
β
sheets.
