Biomedical Engineering Reference
In-Depth Information
*
*
n
OH
1.31 Polyvinyl alcohol.
hydrolysis of polyvinyl acetate. Vinyl alcohol does not exist in nature, since it
becomes acetaldehyde because of keto-enol tautomerism. PVa is composed
mainly of 1,3-diol units, with a very small amount of head-to-head 1,2-diol
units (Fig. 1.31). This material has a great number of applications in the
industrial field, and it is also bioresorbable and non-toxic. These features
make PVa suitable for biomedical applications; indeed, it has been tested for
the synthesis of PVA-based hydrogels or films for drug delivery (Matsumura,
2005).
1.9 References
abe, H. & Doi, Y. 2005. Molecular and material design of polyhydroxyalkanoates (PHas).
Biopolymers Online , Part 3b. Polyesters.
albertsson, a. C. & Varma, i. K. 2005. aliphatic polyesters. Biopolymers Online , Part
4. Polyesters.
allcock, H. r. & ambrosio, a. M. a. 1996. synthesis and characterization of pH-sensitive
poly(organophosphazene) hydrogels. Biomaterials , 17 , 2295-2302.
allcock, H. r., Fuller, T. J. & Matsumura, K. 1982. Hydrolysis pathways for
aminophosphazenes. Inorganic Chemistry , 21 , 515-521.
allcock, H. r. & Kwon, s. 1988. Glyceryl polyphosphazenes: synthesis, properties, and
hydrolysis. Macromolecules , 21 , 1980-1985.
allcock, H. r., Pucher, s. r. & scopelianos, a. G. 1993. Poly[(amino acid ester)
phosphazenes] as substrates for the controlled release of small molecules. Biomaterials ,
15 , 563-569.
ambrosio, a. M. a., allcock, H. r., Katti, D. s. & laurencin, C. T. 2002. Degradable
polyphosphazene/poly(alpha-hydroxyester) blends: degradation studies. Biomaterials ,
23 , 1667-1672.
Batycky, r. P., Hanes, J., langer, r. & edwards, D. a. 1997. a theoretical model of
erosion and macromolecular drug release from biodegrading microspheres. Journal
of Pharmaceutical Sciences , 86 , 1464-1477.
Bourke, s. l. & Kohn, J. 2003. Polymers derived from the amino acid l-tyrosine:
polycarbonates, polyarylates and copolymers with poly(ethylene glycol). Advanced
Drug Delivery Reviews , 55 , 447-466.
Cho, s. Y. & allcock, H. r. 2007. Dendrimers derived from polyphosphazene-
poly(propyleneimine) systems: encapsulation and triggered release of hydrophobic
guest molecules. Macromolecules , 40 , 3115-3121.
Deng, M., Kumbar, s. G., Wan, Y. Q., Toti, U. s., allcock, H. r. & laurencin, C. T.
2010. Polyphosphazene polymers for tissue engineering: an analysis of material
synthesis, characterization and applications. Soft Matter , 6 , 3119-3132.
￿ ￿ ￿ ￿ ￿ ￿
Search WWH ::




Custom Search