Biology Reference
In-Depth Information
Chapter 12
Mechanism-based Clustering of Genome-wide RNA Levels: Roles of
Transcription and Transcript-Degradation Rates
Sungchul Ji
Department of Pharmacology and Toxicology, Rutgers University
170 Frelinghuysen Rd., Piscataway, NJ 08855, USA
E-mail: sji@rci.rutgers.edu
W. Art Chaovalitwongse
Department of Industrial and Systems Engineering, Rutgers University
96 Frelinghuysen Rd., Piscataway, NJ 08854, USA
Email: wchaoval@rci.rutgers.edu
Nina Fefferman
DIMACS, Rutgers University
96 Frelinghuysen Rd., Piscataway, NJ 08854, USA
Department of Public Health and Family Medicine, Tufts School of Medicine
Boston, MA, 02111, USA
Email: nina.fefferman@tufts.edu
Wonsuk Yoo
Department of Internal Medicine, Wayne State School of Medicine
4201 St. Antoine St., UHC 4H-30, Detroit, MI 48201, USA
Email: wyoo@med.wayne.edu
Jose E. Perez-Ortin
Department of Biochemistry and Molecular Biology, University of Valencia
Dr. Moliner 50, 46100 Burjassot, Spain
Email: jose.e.perez@uv.es
DNA array techniques invented over a decade ago enable biologists to measure
tens of thousands of mRNA levels in cells simultaneously as functions of envi-
Corresponding Author.
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