Chemistry Reference
In-Depth Information
NHTf
NHTf
Ph
2
P
Ph
2
P
T
N
Cl
H
+
(
R
)-DABNT
f
Pt
Pt
Neutral path
P
Ph
2
Tf
Ph
2
Cl
PPh
2
PPh
2
Pt
(
S
)-
12
(
S
)/(
R
)-
14
Ph
2
P
H
N
Ph
2
P
Cationic path
Cl
H
+
BIPHEP
Pt
2+
Pt
P
Ph
2
H
2
2SbF
-
Ph
2
Cl
NH
2
NH
2
8
(
R
)-
12
(
R
)/(
R
)-
15
(
R
)-DABN
Scheme 8D.18.
(
R
)-
12
(5 mol %)
AgSbF
6
(11 mol %)
F
3
COH
CO
2
Et
O
R
+
R
F
3
C
2
Et
CH
2
Cl
2
, -20°C, 1 h
R = Ph 98% ee (83%)
100% (
E
)
R =
n
-C
3
H
7
98% ee (92%)
100% (
E
)
Scheme 8D.19.
P
h
2
P
Ni
2+
Fe
2X
-
P
Ph
2
16
(5 mol % )
O
O
H
(
R
)-DABN (5.5 mol %)
+
Ph
H
2
Et
CH
2
Cl
2
, r.t., 24 h
Ph
CO
2
Et
16a
: X = SbF
6
16b
: X = ClO
4
Ni[(
R
)-DABN]SbF
6
90% ee (84%)
76% ee (52%)
75% ee (87%)
Scheme 8D.20.
