Chemistry Reference
In-Depth Information
Ar
NH
2
X
O
O
X =
N
P
O
O
N
Ar
MeO
Ar = 2,4,6-(
i
-Pr)
3
C
6
H
2
O
O
cat
(10 mol %)
HOOH (1.1 eq)
R
R
O
Dioxane, 30-50°C
n
n
17 examples
49-84% yield
78-98% ee
H
N
X
NR
2
H
O
O
H
Working model for asymmetric
epoxidation of enones
Scheme 3.55.
R
2
R
2
H
dppm(AuCl)
2
(2.5 mol %)
Ag-PA
1i
(5 mol %)
Benzene, rt
R
1
O
R
3
R
3
R
2
R
2
OH
n
R
1
R
3
R
3
n
R
1
7 examples
79-91% yield
90-99% ee
SO
2
Mes
N
R
2
R
2
H
Ph(CH
3
)
2
PAuCl (5 mol %)
Ag-PA
1i
(5 mol %)
Benzene, rt
R
1
R
3
R
3
R
2
R
2
NHSO
2
Mes
R
1
n
R
1
R
3
R
3
n
R
1
4 examples
73-97% yield
96-99% ee
Scheme 3.56.
