Concept of Bioelectronic Nose - Bioelectronic Nose: Integration of Biotechnology and Nanotechnology - page 17

Fig. 1.7 ( a ) Real-time responses with normalized current changes (ΔI/I 0 = (I − I 0 )/I 0 , where I 0 is the
initial current and I is the instantaneous current) and ( b ) calibration curves of human parathyroid
hormone receptors and conducting polypyrrol nanoparticle (hPTHR-CPPyNP)-based hormone
sensors toward various human parathyroid hormone (hPTH) concentrations (S indicates the nor-
malized current change). ( c ) Real-time responses of the pristine CPPyNP (20 nm) sensor without
hPTHR measured at V SD = 10 mV. Normalized I SD changes upon addition of target (hPTH) and
nontarget (GLP-1, glucagon, and secretin) analytes. ( d ) Selective responses of the hormone sen-
sor using hPTHR-CPPyNP 20 nm toward nontarget (GLP-1, glucagon, and secretin) and target
analytes. (Reprinted from Ref. [ 91 ] with permission from Copyright (2012) American Chemical
Society)
Detailed information about bioelectronic noses is described in this topic. There
are not only basic explanations of concepts ranging from the mechanism of ol-
faction to the principles of sensor platforms, but also various applications that
were recently attempted. Readers can find information about the latest technical
progress on the development of bioelectronic noses and current issues on practical
applications.
Acknowledgments This work was supported by the National Research Foundation of Korea
(NRF) grant funded by the Ministry of Science, ICT & Future Planning (No. 2013003890).