Biomedical Engineering Reference
In-Depth Information
less expensive revision when failures occur, obviating the need for an entirely new prosthesis when
only one part needs to be replaced. On the other hand, modular system has a high chance of corrosion
failure at the Morse tapers and dislodgment at the Morse taper fittings. It can be lengthened only in
certain increments. Modular component system has additional applications: metastatic bone disease,
failure of internal fixation, severe acute fractures with poor bone quality, and failure of total joints with
insufficient bone stock.
Defining Terms
Bone resorption: A type of bone loss due to the greater osteoclastic activity than the osteogenic
activity.
Callus: Unorganized meshwork of woven bone which is formed following fracture of bone to achieve an
early stability of the fracture.
Fibrous membrane: Thin layer of soft tissue which covers an implant to isolate from the body.
Necrosis: Cell death caused by enzymes or heat.
Osseointegration: Direct contact of bone tissues to an implant surface without fibrous membrane.
Osteolysis: Dissolution of bone mineral from the bone matrix.
Primary healing: Bone healing in which union occurs directly without forming callus.
Secondary healing: Bone union with a callus formation.
Stress shielding: Bone is protected from stress by the stiff implant.
Wol f 's law : Bone develops or adapts the structure most suited to resist the forces acting upon it.
References
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joints with bone cement-precoated implants. I. Interfacial strengths. J Biomed Mater Res 16(4):
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Bono, C. M. and Garfin, S. R. 2004. History and evolution of disc replacement. Spine J 4(Suppl 6):
145S-150S.
Brand, R. A. and Rubin, C. T. 1987. Fracture healing. In Scientific Basics of Orthopaedics , 2nd ed. eds.
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Brighton, C. T. 1984. The biology of fracture repair. Instr Course Lect 33:60-82.
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J Bone Joint Surg Am 75(10): 1533-1548.
Callaghan, J. J., Cuckler, J. M., Huddleston, J. I., and Galante, J. O. 2008. How have alternative bearings
(such as metal-on-metal, highly cross-linked polyethylene, and ceramic-on-ceramic) affected the
prevention and treatment of osteolysis? J Am Acad Orthop Surg 16(Suppl 1): S33-S38.
Cameron, H. U. 1994a. Smooth metal-bone interface. In Bone Implant Interface , ed. R. Hurley, pp. 121-
144. St. Louis: Mosby.
Cameron, H. U. 1994b. The implant-bone interface: Porous metals. In Bone Implant Interface , ed. R.
Hurley, pp. 121-144. St. Louis: Mosby.
Capello, W. N. and Bauer, T. W. 1994. Hydroxyapatite in orthopaedic surgery. In Bone Implant Interface ,
ed. R. Hurley, pp. 121-144. St. Louis: Mosby.
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