Chemistry Reference
In-Depth Information
Table 2.2 Relative rates for
-elimination reactions between small pyridoxamine
analogs and chloropyruvic acid.
b
Compound
R
k
rel
1
SCH
2
CH
2
CH
3
1.00
3
NMe
2
4.3
4
SCH
2
CH
2
NMe
2
9.2
5
SCH
2
CH
2
CH
2
NMe
2
2.6
7
6.4
8
5.3
9
2.8
As a whole, the bilayer catalyst composed of
33
,
36
, and Cu(
II
) ions exhibited the high-
est activity for the
-replacement reaction, showing turnover behavior, with k
rel
= 180.
Murakami et al. also found that, for the
b
-replacement reaction carried out in the
33
-
36
vesicular system,
L-
serine and its hydrophobic benzyl ester derivative show com-
b
Scheme 2.8
