Biomedical Engineering Reference
In-Depth Information
H
H
O
O
OO
Acid treatment
Polymerization
on MWCNT surface
Cast on GCE
Remove template
Template
GCE
MWCNT
MIP network
Figure 11.26
h e simplii ed sketch for the construction of MIPCNT on GCE [61].
h e near equilibrium time to adsorb AP on the surface of electrode is
about 9min (Figure 11.26). h e modii ed electrode was used to detect the
concentration of AP with a linear range and detection limit (S/N=3) of
0.01-1.0μM and 6.88 nM, respectively. Finally, the modii ed electrode was
successfully applied to determine AP in the human serum sample and two
brand tablets.
11.2.1.9 TiO
2
Nanotubes
During the recent decades, fascinating inorganic semiconductor titanium
dioxide (TiO
2
) has attracted extensive attention in the photocatalytic area
for decomposition of organic compounds, sterilization, cancer treatment,
etc. due to its good stability and photochemical activity. Recently, Wang
et al.
proposed a MIP thin i lm for photoelectrochemical (PEC) sensing
of lindane molecules constructed by electropolymerizing o-phenylene-
diamine (o-PD) monomer and lindane template molecule on titanium
dioxide nanotubes [62]. h e resulting PEC sensors were characterized by
scanning electron microscopy, ultraviolet (UV)-vis spectra and electro-
chemical impedance spectra (Figure 11.27). Under visible light irradia-
tion, MIP i lm can generate the photoelectric transition from the highest
occupied molecular orbital to the lowest unoccupied molecular orbital,
delivering the excited electrons to the conduction band of titanium diox-
ide nanotubes. Simultaneously, it is believed that a positive charged hole
(H
+
) of MIP that took part in oxidation process was consumed to promote
the amplifying photocurrent response. h e MIP-based PEC sensor had an
excellent specii city and could be successfully applied to the recognition
and detection of lindane, indicating a promising application in handling
with organochlorine pesticide.
