Biomedical Engineering Reference
In-Depth Information
However there is still a lot of room for research. Particularly, recent i ndings
indicate that the compound delays the wound-healing process and that sil-
ver may have serious cytotoxic activity on various host cells. It is necessary
to examine all available evidence about ef ects, ot en contradictory, of sil-
ver on wound infection control and on wound healing trying to determine
the practical therapeutic balance between antimicrobial activity and cellular
toxicity [115-133]. h e ultimate goal remains the choice of a product with a
superior proi le of infection control over host cell cytotoxicity.
10.6 Conclusion
Owing to their unique properties, metallic nanoparticles i nd wide-range
applications, from medicine and pharmaceutics to electronic industry, optics,
etc. Presently there is great interest for the polymer-metallic nanoparticles
systems in the i eld of biomedical applications based on the need for a system
with a high antibacterial and antiviral activity against bacteria and viruses on
contact, without the release of toxic biocides. h is chapter reports on obtain-
ing metallic nanoparticles such as platinium, gold and silver. It focuses on
obtaining silver nanoparticles, their incorporation within various polymer
materials, a physiochemical and biological property of such obtained sys-
tems as well as about their application as medical devices.
Acknowledgements
M.S. acknowledges the support from the Ministry of Education,
Science
and Technological Development of the Republic of Serbia, under Grant
No. III45004: Molecular designing of nanoparticles with controlled mor-
phological and physicochemical characteristics and functional materials
based on them.
References
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2. Salata O. Applications of nanoparticles in biology and medicine.
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