Chitosan and Low Molecular Weight Chitosan: Biological and Biomedical Applications - Advanced Biomaterials and Biodevices - page 205

Bordetella bronchiseptica
dermonecrotoxin

Nasal,
BALB/c mice

Chitosan
10,100, and 300 kDa,
DDA 90.8 %.

Microspheres
5.23 ± 0.46

[159]

Bordetella bronchiseptica
dermonecrotoxin

Nasal, Mice Mannosylated chitosan

100 kDa; DDA 95.4 %
DS 5.9 mol %.

Microspheres
5.73± 0.42 mm

[160]

Bordetella bronchiseptica
dermonecrotoxin

In vitro,
RAW264.7 cells

Pegylated chitosan
10 kDa, DDA 80.4 %
DS 5-8 mol %

Microspheres
5.47 m m

[161]

Inl uenza A subunit H3N2 Nasal, Mice Trimethyl chitosan

177 kDA, DDA 93 %,
DQ 25 %

Nanoparticles 0.85±0.03mm [162]

Tat toxoid Nasal, Mice Chitosan Nanoparticles [163]

Helicobacter pylori urease and
muramyl di-peptide

Nasal, intramuscular,
BALB/c mice

Chitosan Solution [164]

GM-CSF Subcutaneous, Mice Chitosan Solution [165]

PEI- DNA complex (hepatitis B) Intramuscular,

BALB/c mice

Mannosylated chitosan
102 kDa; DDA 85 %
DS 0.3

Microspheres
86.6±30.2 nm

[166]

DNA peanut allergen gene
(pCMVArah2)

Oral, Mice Chitosan ~390 kDa Nanoparticles

150-300 nm

[167]

Plasmid DNA (Respiratory
syncytial virus)

Nasal, BALB/c mice Chitosan Nanoparticles

300-330 nm

[168]

( Continued )