Pseudogenes and their formation - Human Gene Evolution - page 271

Table 6.2 (continued)

Pseudogene Chromosomal location/comments Reference

Uracil-DNA glycosylase Located on chromosomes 14 and 16. Lund et al . (1996)

(2) Unlinked to functional source gene

UNG (12q23-q24)

Tropomyosin, non-muscle MacLeod and Ta bot (1983)

Zinc finger protein ZNF75 12q13. Unlinked to functional source Villa et al . (1996)

gene ZNF75 (Xq26)

Adenylate kinase 3 Located within intron 10 of NF1 Xu et al . (1992)

gene at 17q11.2

Nucleotide excision Chromosome 2. Unlinked to functional Johnson and Campbell

repair protein RAD52 source gene RAD52 (12p12-q13) 1996)

Serotonin 5- Transcribed. Capable of being Nguyen et al . (1993);

hydroxytryptamine 1D translated into 28 amino acid. Bard et al . (1995)

receptor polypeptide. Unlinked to functional
source gene HTR1D (1p34-p36)
Fatty acid-binding 13q13-q14. Unlinked to functional source Prinsen et al . (1997)
protein 3 gene FABP3 (1p32-p33).
Cysteine and glycine- 3q21. Unlinked to functional source gene Weiskirchen et al . (1997)
rich protein 2 CSRP2 (12q21).
c-Ki- ras 1 proto-oncogene 6p12-p11. Unlinked to functional source McGrath et al . (1983)

gene KRAS2 (12p12).

c- elk -1 proto-oncogene 14q32 within IGHV locus. Unlinked to Harindranath et al .

(2) functional source gene ELK1 (Xp11.2). (1998)

Insertion occurred 30-60 Myrs ago
prior to IGHV locus duplication.

Interleukin-6 signal 17p11. Unlinked to functional source Rodriguez et al . (1995)

transducer gene IL6ST (5q11).

SHC transforming Xq12-q13. Unlinked to functional Harun et al . (1997)

protein source gene SHC1 (1q21).

Mitochondrial-3-glycerol Chromosome 17. Unlinked to functional Brown et al . (1996)

phosphate source gene GPD2 (2q24)

dehydrogenase 2
Mitochondrial elongation 17q11. Unlinked to functional source Ling et al . (1997)

factor Tu gene TUFM (16p11)

Mitochondrial NADH: 19q13.3-qter. Unlinked to functional de Coo et al . (1995)

ubiquinone source gene NDUFV2 (18p11.2-p11.31).

oxidoreductase 24-kDa Partially processed.

subunit
NADH: ubiquinone oxido 11p15. Unlinked to functional source

Russell et al . (1997)

reductase B13 subunit gene NDUFA5 (7q32)

Solute carrier family 9 Chromosome 10. Unlinked to functional Kokke et al . (1996)

(NHE3) source gene SLC9A3 (5p15)

B- raf Xq13. Unlinked to functional source Eychene et al . (1992)

gene BRAF (7q34)

GTP-binding protein G q 2q14-q21. Unlinked to functional source Dong et al . (1995)

gene GNAQ (9q21)

E-catenin 5q22 [Unlinked to functional Nollet et al . (1995)

source gene CTNNA1 (5q11)