Pseudogenes and their formation - Human Gene Evolution - page 270

Pseudogene Chromosomal location/comments Reference

28S ribosomal RNA Flanked by 16 bp direct repeats Wang et al . (1997)

Ribosomal protein L23A Chromosome 13. Unlinked to de Fatima Bonaldo et al .

functional source gene RPL23A (17q11) (1996)

Ribosomal protein L38 Located in promoter region of type-1 Espinosa et al . (1997)

angiotensin II receptor gene ( AGTR1 ;
3q21-q25)

Ferritin L (5) Unlinked to functional source gene Santoro et al . (1986)

FTL (19q13).

Ferritin H (18) Highly dispersed (1p, 1q, 2q, 3q, 4, 6p, Dugast et al . (1990);

13q, 14, 17p, X). Unlinked to functional Zheng et al . (1995; 1997)

source gene FTH1 (11q12-q13).

Glyceraldehyde-3- Dispersed including Xp21-p11. Not linked Arcari et al . (1989)

phosphate to functional source gene GAPD (12p13).

dehydrogenase (5)
Cytochrome c oxidase

Unlinked to functional source gene Taanman et al . (1991)

subunit VIb (3) COX6B (19q13)

Cytochrome b 5 (2) Partial. Transcribed. 14q31-q32 and Giordano et al . (1993)

20p11. Unlinked to functional source
gene CYB5 (18q23).

Prothymosin (5) Unlinked to functional source gene Manrow et al . (1992)

PTMA (chromosome 2). Not transcribed.

Argininosuccinate Highly dispersed. Originated during last Nomiyama et al . (1986);

synthetase (14) 40 Myrs. Unlinked to functional source Freytag et al . (1984)

gene ASS (9q34).

Immunoglobulin J Chromosome 8q13-q21. Unlinked to Max et al . (1994)

functional source gene IGJ (4q21).
Originated ~40-50 Myrs ago.

Immunoglobulin Present in Old World monkeys and Ueda et al . (1985)

gorilla but appears to have been lost
in chimpanzee.

Immunoglobulin Unlinked to functional source Hollis et al . (1982)

immunoglobulin genes IGLC1 (22q11).

Calmodulin (5) Unlinked to functional source gene Koller et al . (1991);

CALM1 (14q24-q31). Originated ~21-49 Rhyner et al . (1994)

Myrs ago.

Phosphoglycerate kinase McCarrey (1990)

Metallothionein Karin and Richards (1982)

-Actin (3) Chromosomes 6, 15 and 18. Unlinked to Moos and Gallwitz (1982;

functional source gene ACTB (7p22) 1983); Ueyama et al . (1996)

-Actin (3) Chromosomes 3q23, 20p13, 6p21. Ueyama et al . (1996)

Unlinked to functional source gene
ACTG1 (17q25)

-Tubulin 8q21-8pter. Unlinked to functional Wilde et al . (1982a);

source gene TUBB (6p21-pter). (1982b); Floyd-Smith

et al . (1986)

Laminin receptor Flanked by 18 bp direct repeats. Not Richardson et al . (1998)

transcribed. Originated 3.5-5 Myrs ago.

Enolase 1 Chromosome 1q41-q42. Unlinked to Ribaudo et al . (1996)

functional source gene ENO1 (1p36-pter)