Information Technology Reference
In-Depth Information
Chapter 2
A Prototype of Translational
Informatics in Action
Philip R. O. Payne
By the End of this Chapter, Readers Should Be Able To
Understand the multiple types and levels of stakeholders, and their respective
activities that can and should be impacted by the Translational Informatics
paradigm;
Describe an exemplary clinical scenario that illustrates the scope and impact of
Translational Informatics on the delivery of knowledge driven healthcare; and
Apply the preceding context to subsequent chapters that explore various dimen-
sions of the tight coupling of Biomedical Informatics and the domains of bio-
medical research and clinical care delivery in order to achieve the vision of
Translational Informatics.
2.1
Introduction
As was presented in Chap.
1
, the vision for Translational Informatics (TI) is predi-
cated on three critical and synergistic dimensions, namely:
1. The promise of translational science, particularly as applied to biomedicine [
1
,
2
] ;
2. An emergent trend away from reductionism and towards systems thinking [
3
-
5
];
and
3. The formalization of a central dogma for the broad domain of Biomedical
Informatics.
These dimensions have broad ranging and signifi cant impacts on a variety
of actors and their activities that serve to make up the biomedical research and
Search WWH ::
Custom Search