An Introduction to Translational Informatics and the Future of Knowledge-Driven Healthcare - Translational Informatics: Realizing the Promise of Knowledge-Driven Healthcare - page 17

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Additional Reading
Ahn AC, Tewari M, Poon CS, Phillips RS. The limits of reductionism in medicine: could systems
biology offer an alternative? PLoS Med. 2006;3(6):709-13.
Ash JS, Anderson NR, Tarczy-Hornoch P. People and organizational issues in research systems
implementation. J Am Med Inform Assoc. 2008. PubMed PMID: 18308986.
Auffray C, Chen Z, Hood L. Systems medicine: the future of medical genomics and healthcare.
Genome Med. 2009;1(1):2.1-2.11.
Barabasi AL, Oltvai ZN. Network biology: understanding the cell's functional organization. Nat
Rev Genet. 2004;5:101-13.
Cantor MN. Translational informatics: an industry perspective. J Am Med Inform Assoc.
2012;19(2):153-5. PubMed PMID: 22237867. Pubmed Central PMCID: 3277629.
Embi PJ, Payne PR. Clinical research informatics: challenges, opportunities and defi nition for an
emerging domain. J Am Med Inform Assoc. 2009;16(3):316-27. PubMed PMID: 19261934.
Epub 2009/03/06.
Embi PJ, Payne PR. The role of biomedical informatics in facilitating outcomes research: current
practice and future directions. Circulation. 2009;120:2393-9.
Hood L, Friend SH. Predictive, personalized, preventive, participatory (P4) cancer medicine. Nat
Rev Clin Oncol. 2010;8:184-7.
Kohane IS, Churchill SE, Murphy SN. A translational engine at the national scale: informatics for
integrating biology and the bedside. J Am Med Inform Assoc. 2012;19(2):181-5. PubMed
PMID: 22081225, Pubmed Central PMCID: 3277623.
Lussier YL, Chen JL. The emergence of genome-based drug repositioning. Sci Transl Med.
2011;3(96):1-3.
Payne PR, Embi PJ, Sen CK. Translational informatics: enabling high throughput research para-
digms. Physiol Genomics. 2009;39:131-40.
Payne PR, Johnson SB, Starren JB, Tilson HH, Dowdy D. Breaking the translational barriers: the
value of integrating biomedical informatics and translational research. J Investig Med.
2005;53(4):192-200. PubMed PMID: 15974245. Epub 2005/06/25. eng.