Information Technology Reference
In-Depth Information
10.3.3.2
Key Stakeholders and Factors Essential
to Operationalizing EGM
By advancing EGM we achieve and evidence cycle that is essential to altering the
research-practice paradigm. This new paradigm informs the work of various stake-
holders, from individual researchers, practitioners, and the public, to institutions,
government agencies and private-sector concerns. Once recognized as the prevail-
ing paradigm, all such stakeholders can begin to see they have a role in advancing
the evidence cycle - including research and translation.
To operationalize EGM, there are a range of enabling factors that span these
stakeholders. These include policy and organizational factors, fi scal and administra-
tive factors, and Informatics and Health IT factors [ 25 ].
10.3.3.3
Implications of Adopting and Operationalizing EGM
Adopting EGM and creating the evidence cycle enables us to address the challenges
facing our research and healthcare enterprises. Indeed with EGM in mind the creation
of a learning health system becomes not only something that would be nice to have but
something that is essential to an effective and effi cient health system. Moreover, in
order to create an evidence cycle as required by such a paradigm, the various goals of
technological, organizational, and cultural changes must take place. As a result, changes
to align policies and resources should be made that will improve the efforts of those
working to advance translational informatics and create learning health systems.
10.4
Conclusion
Realizing the promise of translational informatics requires a signifi cant amount of
coordinated effort and change. In addition to advancing technologies changes to
organizational structures regulatory and policy frameworks as well as cultural
changes must take place. However the momentum to do so is clearly in place and we
have never been better position to realize the vision of translational informatics and
knowledge driven healthcare as we are today. By following the frameworks and
paradigms laid out above the promise of translational informatics to signifi cantly
improve personalized and precision medicine is within our grasp.
Discussion Points
￿ How can the theories and methods that comprise Translational Informatics con-
tribute to the creation of a learning health system?
￿ What challenges and opportunities exist relative to aligning technical capabilities
with motivating problems for designing an informatics “ecosystem”?
￿ What important socio-cultural barriers need to be overcome in order to opera-
tionalize science, rapid cycle translation, and systems thinking?
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