Information Technology Reference
In-Depth Information
Chapter 1
An Introduction to Translational Informatics
and the Future of Knowledge-Driven
Healthcare
Philip R. O. Payne and Peter J. Embi
By the End of This Chapter, Readers Should Be Able to :
￿
D e fi ne grand challenges and opportunities surrounding emerging trends in bio-
medical research and healthcare delivery, with a focus on the data, information,
and knowledge needed to achieve the vision of such a healthcare model;
￿
Understand important trends related to the need for and potential barriers to creating
and sustaining a learning healthcare system in which systems-thinking and preci-
sion medicine become normative approaches to both research and care delivery; and
￿
Discuss future directions for the fi eld of translational informatics with a particu-
lar emphasis on the technology, cultural, and policy issues that must be addressed
to realize the promise of knowledge-drive healthcare.
1.1
Introduction
The fi eld of biomedicine has undergone, and continues to undergo, massive and
some might argue tectonic changes, particularly over the past decade. At the core of
these changes is a confl uence of trends related to the ways in which biomedical
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