RECENT PROGRESS AND PROSPECTS ON PLANT-DERIVED ANTI-HIV AGENTS AND ANALOGS - Medicinal Chemistry of Bioactive Natural Products - page 393

24. Xie, L.; Takeuchi, Y.; Cosentino, L. M.; McPhail, A. T.; Lee, K. H. Anti-AIDS agents 42.

Synthesis and anti-HIV activity of disubstituted (3 0 R,4 0 R)-3 0 ,4 0 -di-O-(S)-camphanoyl-
( þ )-cis-khellactone analogues. J. Med. Chem., 2001, 44: 664-671.

25. Xie, L.; Takeuchi, Y.; Cosentino, L. M.; Lee, K. H. Anti-AIDS agents 37. Synthesis and

structure-activity relationships of (3 0 R,4 0 R)-( þ )-cis-khellactone derivatives as novel
potent anti-HIV agents. J. Med. Chem., 1999, 42: 2662-2672.

26. Beller, M.; Sharpless, K. B. Diols via catalytic dihydroxylation. In Cornils, B.; Herrmann,

W. A. editors. Applied Homogeneous Catalysis with Organometallic Compounds, vol. 3,
2nd Edition. Weinheim, Germany: Wiley-VCH, 2002, 1149-1164.

27. Mehltretter, G. M.; Dobler, C.; Sundermeier, U.; Beller, M. An improved version of the

Sharpless asymmetric dihydroxylation. Tetrahedron Lett., 2000, 41: 8083-8087.

28. Kolb, H. C.; VanNieuwenhze, M. S.; Sharpless, K. B. Catalytic asymmetric dihydrox-

ylation. Chem. Rev., 1994, 94: 2483-2547.

29. Becker, H.; Sharpless, K. B. A new ligand class for the asymmetric dihydroxylation of

olefins. Angew. Chem., Int. Ed. Engl, 1996, 35: 448-451.

30. Xie, L.; Crimmins, M. T.; Lee, K. H. Anti-AIDS agents 22. Asymmetric synthesis of

3 0 ,4 0 -di-O-( )-camphanoyl-( þ )-cis-khellactone (DCK), a potent anti-HIV agent. Tetra-
hedron Lett., 1995, 36: 4529-4532.

31. Xia, Y.; Yang, Z. Y.; Brossi, A.; Lee, K. H. Asymmetric solid-phase synthesis of

(3 0 R,4 0 R)-di-O-cis-acyl 3-carboxyl khellactones. Org. Lett., 1999, 1: 2113-2115.

32. Takeuchi, Y.; Xie, L.; Cosentino, L. M.; Lee, K. H. Anti-AIDS agents 28. Synthesis and

anti-HIV activity of methoxy substituted 3 0 ,4 0 -di-O-( )-camphanoyl-( þ )-cis-khellactone
(DCK) analogs. Bioorg. Med. Chem, Lett., 1997, 7: 2573-2578.

33. Xie, L.; Takeuchi, Y.; Cosentino, L. M.; Lee, K. H. Anti-AIDS agents 33. Synthesis and

anti-HIV activity of mono-methyl substituted 3 0 ,4 0 -di-O-( )-camphanoyl-( þ )-cis-khel-
lactone (DCK) analogs. Bioorg. Med. Chem, Lett., 1998, 8: 2151-2156.

34. Thornber, C. W. Isosterism and molecular modification in drug design. Chem. Soc. Rev.,

1979, 8: 563-580.

35. Krogsgaard-Larsen, P.; Hjeds, H.; Curtis, D. R.; Lodge, D.; Johnston, G. A. R.

Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogs.
J. Neurochem., 1979, 32: 1717-1724.

36. Yang, Z. Y.; Xia, Y.; Xia, P.; Cosentino, L. M.; Lee, K. H. Anti-AIDS agents 31. Synthesis

and anti-HIV activity of 4-substituted 3 0 ,4 0 -di-O-( )-camphanoyl-( þ )-cis-khellactone
(DCK) thiolactone analogs. Bioorg. Med. Chem, Lett., 1998, 8: 1483-1486.

37. Cava, M. P.; Levinson, M. I. Thionation reactions of Lawesson's reagents. Tetrahedron,

1985, 41: 5061-5087.

38. Yang, Z. Y.; Xia, Y.; Xia, P.; Brossi, A.; Cosentino, L. M.; Lee, K. H. Anti-AIDS agents

41. Synthesis and anti-HIV activity of 3 0 ,4 0 -di-O-( )-camphanoyl-( þ )-cis-khellactone
(DCK) lactam analogues. Bioorg. Med. Chem. Lett., 2000, 10: 1003-1005.

39. Xie, L.; Yu, D.; Wild, C.; Allaway, G.; Turpin, J.; Smith, P. C.; Lee, K. H.

Anti-AIDS agents 52. Synthesis and anti-HIV activity of hydroxymethyl (3 0 R,4 0 R)-
3 0 ,4 0 -di-O-(S)-camphanoyl-( þ )-cis-khellactone derivatives. J. Med. Chem., 2004, 47:
756-760.

40. Xie, L.; Allaway, G.; Wild, C.; Kilgore, N.; Lee, K. H. Anti-AIDS agents 47. Synthesis

and anti-HIV activity of 3-substituted 3 0 ,4 0 -di-O-(S)-camphanoyl-(3 0 R,4 0 R)-( þ )-cis-khel-
lactone derivatives. Bioorg. Med. Chem. Lett., 2001, 11: 2291-2293.