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OH
O
HO
O
OH
OR
OH
OH
Sarcophytol-C (
7
)
R=H, Sarcophytol-A (
3
)
R=Ac, Sarcophytol-A
acetate (
4
)
Sarcophytol-B (
5
)
Sarcophytonin A (
6
)
Sarcophytol-D (
8
)
RO
OH
OH
OH
OH
OH
OR
OH
HO
Sarcophytol-E (
9
)
Sarcophytol-F (
10
)
Sarcophytol-G (
11
)
R=H, Sarcophytol-H (
12
)
R=Ac, Sarcophytol-H
acetate (
13
)
Sarcophytol-I (
14
)
HO
OH
OH
OH
OH
OH
OH
Sarcophytol-J (
15
)
Sarcophytol-K (
16
)
Sarcophytol-M (
17
)
Serratol (
18
)
Sarcophytol-N (
19
)
OH
HO
HO
HO
OH
OH
OH
OH
OR
OH
OH
Sarcophytol-O (
20
)
Sarcophytol-P (
21
)
Sarcophytol-Q (
22
)
Sarcophytol-R (
23
)
Sarcophytol-S (
24
)
OH
OH
OH
Sarcophytol-T (
25
)
in 1990
Sarcophytol-T (
26
)
in 1998
Figure 6-2
and sarcophytol O (20), in addition to two known cembranoids, (
)-nephthenol
(40) and sinulariol D (74), were reported as being isolated from the soft coral
S. glaucum.
10
The structures were determined by spectroscopic data and chemi-
cal conversion; sarcophytol M (17) was found to be the enantiomer of the known
compound cembrenol, serratol (18). Six new cembranoids, sarcophytol F (10), K
(16), P (21), Q (22), R (23), and S (24) together with sarcophytol B (5), C (7), D
(8), E (9), G (11), H (12), I (14), J (15), M (17), N (19), and O (20) were reported
coming from a Japanese species.
11
Sarcophytol P (21) was shown to be the
20-hydroxy derivative of sarcophytol A (3); sarcophytol R (23) and S (24) were cor-
related with sarcophytol A (3) by conversion of its 7R,8R and 7S,8S epoxide
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