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297. Ginsburg, H.; Famin, O.; Zhang, J.; Krugliak, M. Inhibition of glutathione-dependent
degradation of heme by chloroquine and amodiaquine as a possible basis for their
antimalarial mode of action. Biochem. Pharmacol., 1998, 56(10): 1305-1313.
298. Famin, O.; Krugliak, M.; Ginsburg, H. Kinetics of inhibition of glutathione-mediated
degradation of ferriprotoporphyrin IX by antimalarial drugs. Biochem. Pharmacol.,
1999, 58(1): 59-68.
299. Schirmer, R. H.; Muller, J. G.; Krauth-Siegel, R. L. Disulfide-reductase inhibitors as
chemotherapeutic agents: the design of drugs for trypanosomiasis and malaria. Angew.
Chem. Int. Ed. Engl., 1995, 34: 141-154.
300. Wu, W.-M.; Chen, Y.-L.; Wu, Y.-L. to be published.
301. Eckstein-Ludwig, U.; Webb, R. J.; van Goethem, I. D. A.; East, J. M.; Lee, A. G.;
Kimura, M.; O'Neill, P. M.; Bray, P. G.; Ward, S. A.; Krishna, S. Artemisinins target the
SERCA of Plasmodium falciparum. Nature, 2003, 424(6951): 957-961.
302. Robert, A.; Cazelles, J.; Meunier, B. Characterization of the alkylation product of heme
by the antimalarial drug artemisinin. Angew. Chem. Int. Ed., 2001, 40(10): 1954-1957.
303. Robert, A.; Coppel, Y.; Meunier, B. Alkylation of heme by the antimalarial drug
artemisinin. Chem. Commun., 2002, 5: 414-415.
304. Kannan, R.; Sahal, D.; Chauhan, V. S. Heme-artemisinin adducts are crucial mediators
of the ability of artemisisnin to inhibit heme polymerization. Chem. Biol., 2002, 9(3):
321-332.
305. Haynes, R. K.; Monti, D.; Taramelli, D.; Basilico, N.; Parapini, S.; Olliaro, P.
Artemisinin antimalarials do not inhibit hemozoin formation. Antimicrob. Agents
Chemother., 2003, 47(3): 1175-1175.
306. Wu, J.-A.; Ji, R.-Y. A quantitative structure-activity study on artemisinin analogs.
Zhongguo Yaoli Xuebao, 1982, 3(1): 55-60.
307. Haynes, R. K. Artemisinin and derivatives—the future for malaria treatment. Curr. Opin.
Infect. Dis., 2001, 14(6): 719-726; Haynes, R. K.; Ho, W.-Y.; Tsang, H. W. Abstract of
The Third International Symposium for Chinese Medicinal Chemists, Hong Kong,
Dec. 28-31, 2002, 13.
308. Haynes, R. K.; Ho, W.-Y.; Chan, H.-W.; Fugmann, B.; Stetter, J.; Croft, S. L.; Vivas, L.;
Peters, W.; Robinson, B. L. Highly antimalaria-active artemisinin derivatives: Biological
activity does not correlate with chemical reactivivty. Angew. Chem. Int. Ed., 2004, 43:
1381-1385.
309. Sibmooh, N.; Udomsangpetch, R.; Kijjoa, A.; Chantharaksri, U.; Mankhetkorn, S.
Redox reaction of artemisinin with ferrous and ferric ions in aqueous buffer. Chem.
Pharm. Bull. Tokyo, 2001, 49(12): 1541-1546.
310. Wu, Y. K. How might qinghaosu (artemisinin) and related-compounds kill the intraer-
ythrocytic malaria parasite—a chemists view. Account. Chem. Res., 2002, 35(5):
255-259.
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