Chemistry Reference
In-Depth Information
159. Jordan, M. A.; Wilson, L. Microtubules and actin filaments-dynamic targets for cancer
chemotherapy. Curr. Opin. Cell. Biol., 1998, 10: 123-130.
160. Nogales, E.; Wolf, S. G.; Downing, K. H. Structure of the b-tubulin dimer by electron
crystallography. Nature, 1998, 391: 199-203.
161. Rao, S.; He, L.; Chadravarty, S.; Ojima, I.; Orr, G. A.; Horwitz, S. B. Characterization of
the Taxol binding site on the microtubule: identification of Arg282 in b-tubulin as the site
of photoincorporation of a 7-benzophenone analogue of Taxol. J. Biol. Chem., 1999, 31:
37990-37994.
162. Li, Y.; Poliks, B.; Cegelski, L.; Poliks, M.; Gryczynski, Z.; Piszczek, G.; Jagtap, P. G.;
Studelska, D. R.; Kingston, D. G. I.; Schaefer, J., Bane, S. Conformation of microtubule-
bound palictaxel determined by fluorescence spectroscopy and REDOR NMR. Bio-
chemistry, 2000, 29: 281-291.
163. Chatterjee, S. K.; Barron, D. M.; Vos, S.; Bane, S. Baccatin III induces assemble of
purified tubulin into long microtubules. Biochemistry, 2001, 40: 6964-6970.
164. Andreu, J. M.; Barasoain, I. The interaction of baccatin III with Taxol binding site of
microtubules determined by a homogeneous assay with fluorescent taxoid. Biochemistry,
2001, 40: 11975-11984.
165. He, L.; Jagtap, P. G.; Kingston, D. G. I.; Shen, H.-J.; Orr, G. A.; Horwitz, S. B. A
common pharmacophore for taxol and the epothilones based on the biological activity of
a taxane molecule lacking a C-13 side chain. Biochemisty, 2000, 39: 3972-3978.
166. Li, Y.; Edsall, R., Jr.; Jagtap, P. G.; Kingston, D. G. I.; Bane, S. Equilibrium studies of a
fluorescent palictaxel derivative binding to microtubules. Biochemistry, 2000, 39: 616-
623.
167. Diaz, J. F.; Strobe, R.; Engelborghs, Y.; Souto, A. A.; Andreu, J. M. Molecular
recognition of Taxol by microtubules. J. Biol. Chem., 2000, 275: 26265-26276.
168. Nogales, E.; Whittaker, M.; Milligan, R. A.; Downing, K. H. High-resolution model of
the microtubule. Cell, 1999, 96: 79-88.
169. Lillo, M. P.; Ca˜ adas, O.; Dale, R. E.; Acu˜ a, A. U. Location and properties of the taxol
binding center in microtubules: a picosecond laser study with fluorescent taxoids.
Biochemsitry, 2002, 41: 12436-12449.
170. Lowe, J.; Li, H.; Downing, K. H.; Nogales, E. Refined structure of b-tubulin at 3.5A
resolution. J. Mol. Biol., 2001, 313: 1045-1057.
171. Grob-Meurer, P.; Kasparian, J.; Wade, R. H. Microtubule structure at improved resolu-
tion. Biochemistry, 2001, 40: 8000-8008.
172. Banerjee, A.; Kasmala, L. T. Differential assembly kinetics of a-tubulin isoforms in the
presence of paclitaxel. Biochem. Biophys. Res. Commun., 1998, 245: 349-351.
173. Giannakakou, P.; Gussio, R.; Nogales, E.; Downing, K. H.; Zaharevitz, D.; Bollbuck, B.;
Poy, G.; Sackett, D.; Nicolaou, K. C.; Fojo, T. A common pharmacophore for epothilone
and taxanes: molecular basis for drug resistance conferred by tubulin mutations in
human cancer cells. Proc. Natl. Acad. Sci. USA, 2000, 97: 2904-2909.
174. Snyder, J. P.; Nettles, J. H.; Cornett, B.; Downing, K. H.; Nogales, E. The binding
conformation of Taxol in b-tubulin: A model based on electron crystallographic density.
Proc. Natl. Acad. Sci. USA, 2001, 98: 5312-5316.
175. Ojima, I.; Kuduk, S. D.; Chakravarty, S.; Ourevitch, M.; Begue, J. P. A novel approach to
the study of solution sturctures and dynamic behavior of paclitaxel and docetaxel using
fluorine-containing analogues as probes. J. Am. Chem. Soc., 1997, 119: 5519-5527.
Search WWH ::




Custom Search