Biomedical Engineering Reference
In-Depth Information
Figure 4.3. Continued
4.6 Summary
References
In this chapter, various applications, important
properties, and different types of biodegrad-
able materials that are candidates for use in
orthopedic applications have been reviewed.
For this purpose, both natural materials and
synthetic polymers have been used to fabricate
various types of orthopedic implants that
include simple fi xation devices, scaffolds for
delivery of bioactive molecules, and carriers for
delivery of living cell populations. In many
cases, unique materials or strategies can be
combined to produce a more optimal outcome
that is compatible with the intended purpose.
Even though they are still in the early stage of
development, biodegradable scaffolds have
already proven to aid in the repair of orthope-
dic defects. Thus, further research in this fi eld
holds great promise to effect complete regen-
eration of a variety of orthopedic tissues.
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Acknowledgment
We acknowledge funding from the National Ins-
titutes of Health (R
01
-AR
42639
, R
01
-AR
48756
,
10
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) Growth
factor delivery for tissue engineering. Pharm Res
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and R
) for tissue-engineering appli-
cations using biodegradable polymers.
01
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15164
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504
.
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