Information Technology Reference
In-Depth Information
Chapter 19
Antiepileptic Therapy Reduces Coupling
Strength Among Brain Cortical Regions
in Patients with Unverricht-Lundborg Disease:
A Pilot Study
Chang-Chia Liu, Petros Xanthopoulos, Vera Tomaino, Kazutaka Kobayashi, Basim
M. Uthman, and Panos M. Pardalos
Abstract
The unified myoclonus rating scale (UMRS) has been utilized to assess
the severity of myoclonus and the efficacy of antiepileptic drug (AED) treatment in
patients with Unverricht-Lundborg disease (ULD). Electroencephalographic (EEG)
recordings are normally used as a supplemental tool for the diagnosis of epilepsy
disorders. In this study, mutual information and nonlinear interdependence measures
were applied to the EEG recordings in an attempt to identify the effect of treatment
