Chemistry Reference
In-Depth Information
FIGURE 17.15
The structure and active site of the bromoperoxidase subunit from C. pilulifera. Residues conserved in all vanadium bromo-
and chloroperoxidases are in gray, those that vary in cyan.
(From
Ohshiro et al., 2004
.
Copyright 2004 The Protein Society.)
N(His
404
)
H
HOCl
O
H
2
O
2
O
V
OH
O
N(His
496
)
N(His
404
)
N(His
404
)
H
H
H
H
O
O
-
OOH
O
O
O
V
V
OH
Cl
O
O
OH
N(His
496
)
N(His
496
)
N(His
404
)
Cl
-
O
O
V
Cl
-
H
+
, H
2
O
O
O
- 2H
2
O
N(His
496
)
FIGURE 17.16
Proposed mechanism for the vanadium chloroperoxidase oxidation of chloride by hydrogen peroxide.
(Adapted from
