Chemistry Reference
In-Depth Information
FIGURE 16.9
Structure-based arginase mechanism. (Left) Schematic representation of the arginase mechanism; R-amino and R-carboxylate
substrate groups are omitted for clarity. (Middle, right) Stereo view of the arginase mechanism. Protein atoms are colour-coded as follows: C)
gray, O) red, and N) blue; ligand atoms are colour-coded the same with the exception: C) yellow; water molecules appear as red spheres.
Manganese coordination interactions are designated by red dashed lines and hydrogen bonds by black dashed lines.
(From
Cox et al., 2001
.
Copyright 2001 with permission from the American Chemical Society.)
