Chemistry Reference
In-Depth Information
9.45
In each case, write the structure of the alcohol:
R
2
R
1
COH
R
3
One of the R groups comes from the Grignard reagent. The rest of the molecule
comes from the carbonyl compound. For example, If we select R
1
as the alkyl group
to come from the Grignard reagent, then the carbonyl compound is:
R
2
C
O
R
3
a.
CH
3
OH
O
-
CH
3
O MgX
CH
3
OH
+
H
3
O
C
H
3
MgX
+
For the remaining cases, we will not write the equations, but simply show how
the initial reactants are derived.
b.
H
CH
3
CH
2
C
OH
from
CH
3
CH
2
MgX
+
CH
3
CH
2
CH
2
CH
2
CH
2
CH
O
CH
2
CH
2
CH
2
CH
2
CH
3
c.
CH
3
CH
3
OH
CH
3
MgX
+
CH
3
CCH
2
CH
2
CH
3
O
C
CH
2
CH
2
CH
3
from
or
CH
3
CH
3
CH
2
CH
2
OH
CH
3
CH
2
CH
2
MgX
+
CH
3
C
CH
3
C
from
CH
3
O
Either of these combinations of reagents will work.
d.
HO
from
MgX
+
O
