Biomedical Engineering Reference
In-Depth Information
ferments), regulating the metabolic process and functions of the cells, through the system of
adenylate cyclasa. And finally the above system influences directly the functions of the cells
genome providing for the possibility of new genes expression revealing genes which were
silent before. It also makes possible the emergence of proteins supporting new functions
which lacked before [2]. Concentrated in the growth segments of browses and pollen,
brassinosteriods penetrate the organisms of invertebrates and vertebrates, causing different
specific and general protective effects. The content of brassinosteroids in plants is very low,
hence the chemical synthesis is the only source of such compounds in substantial amounts.
3.
R
ESULTS
We have been carrying out the researches of brassinosteriod properties since 1994.
Currently we are engaged in researches on a number of perspective directions in the
Laboratory of Biotechnologies located in ASU Technology Park (Astrakhan Region,
Privolzhsky District, settlement Nachalo). We are carrying out researches on impact and
development of original preparations on the basis of perspective biologically active
substances (BAS) to increase the survival rate of valuable biological objects, as well as on
implementation of nanoregulators in biological systems vital processes management.
Preparations on the basis of brassinosteroids possess a wide range of stimulatory and
protective properties and thus increase the yield and quality of the agricultural products. Epin-
extra preparation, that is known in Russia and abroad, with epibrassinolide as active
substance, was synthesized at the Chemical Faculty of Moscow State University and
developed as a ready-to-use drug by the colleagues from LLC Non-profit Production
Partnership “NEST M”. This preparation is an effective immune response modifier increasing
the resistance of plants to stress and phytopathogenes. These effects are accomplished by
initiating a sequence of biochemical transformations, such as activation and suppression of
key enzymatic reactions, stimulation of protein synthesis, activation of photosynthesis etc.
[3]. Epibrassinolide, active substance of the preparation, is a natural biological regulator
which is traditionally present in animal and human nutrition and is metabolized in an
evolutionally habitual way. It is an important guarantee of ecological safety of the preparation
and it is proved by its toxicological testing. Furthermore the stimulation of plant natural
resources by the preparation allows diminishing the usage of other protective means for
plants. Preparations on the basis of brassinosteroids can be regarded as a new generation of
environmental friendly agricultural specimens with natural way of impact and measuring that
is comparable to their contents in the natural conditions. Researches on the impact of
brassinosteroids on animals haven't been carried out before.
C
ONCLUSION
We were the first to carry out complex researches on the influence of epibrassinolide on
animals, microorganisms of different level of phylogenesis icluding the ontogenesis aspect [3;
4; 5]. Analyses of lipid peroxidation (LPO), permeability of blood-tissue interface (PBTI) as
well as some other biochemical parameters of blood prove the absence of real pathologic
Search WWH ::
Custom Search