Biomedical Engineering Reference
In-Depth Information
Studies on optimization of Bacinil application schedule have shown that the best strategy
envisages intake of 15-20 ml doses twice a day for 3 sequential days. The above-mentioned
dosage and application procedure enable to rehabilitate 100% of sick calves within 2 days.
To optimize therapy of enteritis cases in piglets, 5 test groups with gastrointestinal
problems were formed, each comprising 25-30 heads aged up to 25 days. The experiments
demonstrated that optimal single Bacinil dose is 1.5-2.0 ml. It cuts recovery of piglets by 43-
45% and decreases mortality rate by 86%.
Administration of probiotic at optimal doses once per diem during 3 consecutive days
curtails rehabilitation period by 47-60% in piglets, while Bacinil application twice a day for
72 hours ensures 100% elimination of pathological symptoms.
Based on completed investigations provisional regulations for application of Bacinil to
prevent and treat diseases of young farm stock - calves and piglets were compiled.
Large-scale trials of Bacinil efficiency were conducted at Belarusian farms. Pilot-plant
Bacinil batch in amount of 1000 doses was produced for further farm tests guided by
provisional application regulations.
To study therapeutic efficiency of probiotic Bacinil upon young cattle treatment at
Vishnyovka bull-rearing complex in Minsk region, 2 groups of calves aged 40-60 days were
formed. Experimental group was subjected to Bacinil treatment at dose 15 ml/per head until
complete rehabilitation. Additionally conventional therapy schemes were used. In contrast,
Bacinil was not administered to control group. Rehabilitation was assumed to be completed
when symptoms of respiratory diseases disappeared. Clinical monitoring of animals was
carried out during 14 days. Therapeutic efficiency of probiotic was assessed via duration of
pathological process and mortality rate of young stock. Experimental results are presented in
table 3.
To evaluate prophylactic efficiency of Bacinil in preventing respiratory diseases of young
cattle 2 groups of calves aged 14-20 days were made up. Test group was fed Bacinil at dose
10 ml/head during 7 days. Probiotic was not supplied to the control group. Clinical survey of
farm animals occurred for 14 days, including thermometry, general control, feed intake.
Prophylactic efficiency of Bacinil was evaluated via incidence of pathologies in young stock.
Experimental data are illustrated in table 4.
Table 3. Therapeutic efficiency of Bacinil upon treatment of respiratory diseases in
young cattle
Animal
groups
Recovery rate, %
Mortality rate
Number of
animals
Duration of
pathology, days
Therapeutic
efficiency, %
heads
%
heads
%
Test
60
3.5
58
96.6
2
3.4
96.6
Control
40
8.3
25
64.5
15
35.5
-
Table 4. Preventive efficiency of Bacinil with respect to respiratory diseases
of young cattle
Animal groups
Number of
animals
Disease cases
Mortality rate
Prephylactic
efficiency
heads
%
heads
%
Experimental
20
1
5.0
-
-
95.0
Control
15
3
15.0
-
-
-
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