Modeling Proteins at the Interface of Structure, Evolution, and Population Genetics - Computational Modeling of Biological Systems - page 359

the process of molecular evolution. The three current research trajectories have
developed more independently than would be desirable, as models from each
subfield can be useful in other subfields. Further, incorporation of population
genetic models into molecular evolution is more advanced than the incorporation of
structural and functional considerations. However, it is with this growing multiscale
modeling trajectory that a key understanding of the evolution of cell and molecular
systems can be generated, both in the details and in the processes.
Acknowledgements D.A.L. is funded by NSF DBI-0743374 and NIH-INBRE award P20
RR016474. A.I.T. is supported by the aforementioned NSF award, while J.A.G. is supported by
the aforementioned NIH-INBRE award.
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