Biomedical Engineering Reference
In-Depth Information
Fig. 1 Flowchart of the steps followed in the construction of a comparative structural model
( database)
2
Template Identification
2.1
Domain Delineation
One of the first steps to be performed with the query sequence is to determine
the number of domains in the sequence. In many multidomain proteins, a single
structural template covering the whole sequence may not be available. Instead,
templates for each of the domains may be available. Many programs that employ
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